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Journal of Speech and Hearing Research Vol.39 968-980 October 1996.
© American Speech-Language-Hearing Association
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Longitudinal Phonatory Characteristics After Botulinum Toxin Type A Injection

Kimberly V. Fisher 1
Ronald C. Scherer 2
Chwen G. Guo 2

Ann S. Owen 1
1 University of Oklahoma Health Sciences Center Oklahoma City
2 Denver Center for the Performing Arts Denver, CO

kfi663{at}nwu.edu

Following Botulinum Toxin Type A injection, glottal competency of an adductor spasmodic dysphonia patient is thought to vary over a wide range. This study quantifies variability in laryngeal adduction for one such patient over a 10-week period. Analyses of kinematic and aerodynamic measures were used to track the voice weekly. The measures included the electroglottographic waveform width (EGGW50), nondimensional electroglottographic slope quotient (SLQ), glottal flow open quotient (FOQ), dc glottal flow, and nondimensional glottal flow peak quotient (FPQ). The results suggested that change in degree of glottal adduction over time can be observed even when vocal instability is present within each recording session. Perceptual ratings of vocal quality (breathy to pressed) were related to the laryngeal measures. The coefficient of variation for EGGW50 and the percentage of dichrotic phonations reached minima during sessions with predominantly breathy and hypoadducted phonation. The methods used in this study show potential to aid decisions about dose level and sources of perceptual adductor spasmodic dysphonia symptoms for a given patient.

KEY WORDS: voice disorders, spasmodic dysphonia, Botulinum Toxin, electroglottography, inverse filtering

Submitted on March 20, 1996
Accepted on April 18, 1996


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